FAN: fingerprint analysis of nucleotide sequences

FAN is a server for fingerprint analysis of nucleotide sequences. The server performs a search of submitted nucleotide sequences against the PRINTS database. Searches are performed directly against fingerprints using a codon position specific score matrix (PSSM) approach. The advantages of this approach are increased specificity for coding sequence (CDS) over non-CDS, and increased tolerance to base-substituting and frameshifting sequence errors. Furthermore, there is no need for prior translation of the nucleotide sequences. A web-based interface to the software is available at http://bioinf.man.ac.uk/cgi-bin/neil/ntfront.pl.